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Etizolam (also known by the brand names Etilaam, Etizest) is in the class of thienodiazepines, related to benzodiazepines. It works by binding to GABA receptors in the brain.

Etizolam is not commonly prescribed in France. It is sold online as research chemicals and is commonly used as a substitute for pharmaceutical benzodiazepines such as alprazolam (Xanax) or diazepam (Valium).

Etizolam is classified as a psychotropic substance

Etizolam first appeared on the online research chemicals market in 2011. Since then, its popularity has grown steadily. This is likely due to both its low cost, its abundance, as well as its slightly euphoric effects.

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Etizolam differs from most other research chemicals in that it is approved and actively prescribed as a medical treatment for anxiety in many countries, usually under brand names such as Etilaam and Etizest.

Medical papers documenting its use in the treatment of anxiety have been documented as far back as the 1990s.

Appearance, what does it look like?

Etizolam is commonly found in the form of granules, tablets, blotter or as a pure white powder.

" ...if I may say so: the medium, whether it be blotting paper or an aggregate of excipients (tablet), does not create the danger.

I would go so far as to say that powder blenders/blenders to make tablets or capsules are less reliable than diluting in pure alcohol.

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Then given the size of a square of blotter, and the volume of saturated alcohol necessary for 1 or 2mg of etizolam, we do not distribute "a drop" poof like that and basta: it would overflow the paper or spread beyond by capillarity. That's why we use a micro-pipette, and if you want to do things right, you deposit only a fraction of volume (expressed in micro-milliliter µml), then you wait for evaporation, then you start again, and so on several times until you reach the desired concentration on your blotter.

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other names

Etilaam; Etizola; Etizest; Sedekopan; Arophalm; To not; pasaden

Screening test

" And watch out, when I decided to stop I had the right to a urine analysis at the CSAPA to verify that I was indeed addicted to a benzo and the result was negative. Obviously the tests used do not - or not systematically - detect etizolam as a benzo in the urine. It was quite a hassle to prove that yes, I was indeed addicted to a member of the benzo family and that I urgently needed a benzo with a long half-life to get off the hook.

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Dosages

Anecdotal reports suggest that in terms of relative potency, 1 mg of etizolam is equivalent to approximately 0.5 mg of alprazolam (Xanax), 0.5 mg of clonazepam (Klonopin), or 10 mg of diazepam (Valium). It is often compared to a less potent, sedating version of alprazolam in terms of how quickly the effects appear, how long they last, and the recreational effect.

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Having a milligram scale is not enough. When it is received in powder, it must be volumetrically diluted in propylene glycol to be able to consume it. Etizolam is not soluble in water and can lead to disasters if you try to do so: all the powder is suspended above the liquid and in one sip you take it all at once.

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" A few weeks ago, I ordered etizolam powder on a known site (8).

So I received 250 mg. I already know this molecule, but I did an allergy test anyway

Now the serious stuff. As the average dose is 1 mg, dosing is difficult. So I started by mixing about 20 mg in a 0.5 liter bottle.

Vaping

Etizolam can be consumed by vaping it: mixed with propylene glycol, with an electronic cigarette.

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" Etizolam dissolves perfectly in PG and it is possible to add aroma and VG (I tried up to 10% VG), to have a "ready to drink" C-liquid.

It is important to leave a maturation time of at least 48 hours by shaking and degassing (opening the bottle, so that the solution is as homogeneous as possible (up to 1/2 week depending on the aromas, but more to do with the homogeneity).

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" My biggest concern with etizolam in e-liquid form is that it's particularly easy to black out.

I tend to want to pull the extra hit and... I don't remember everything the next day (not to mention that I bump into a lot of furniture and I'm very "dizzy").

I gave up this ROA, I can't manage the craving "which makes me want to go further".

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Without any mixture with another psychotropic product, huh!!!

For Etizolam, I would make B-liquid (Benzo-liquid) dosed at 1 mg/ml, and I would take 2 ml tanks to consume.

This allows the user to know precisely the number of mg he has consumed. 1 tank = 1 tablet of 1 mg.

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Overdose

Thienodiazepine overdose can occur when taken in extremely high amounts or at the same time as other depressants. This is particularly dangerous with other GABAergic depressants such as barbiturates and alcohol because they work similarly, but bind to distinct allosteric sites on the GABAA receptor, so their effects mutually potentiate each other.

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Thienodiazepine overdose is a medical emergency that can lead to coma, permanent brain damage, or death if not treated promptly and correctly.

Symptoms of a thienodiazepine overdose may include deceleration of thought, slurred speech, mental confusion, delusion, respiratory depression, coma, or death.

Tolerance, habituation, dependence

Like all benzodiazepines, etizolam can be highly addictive with physical dependence.

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Tolerance to the sedative-hypnotic effects will develop within two days of continued use. After discontinuation, tolerance returns to baseline within 7-14 days. However, in some cases, it may take much longer, proportional to the duration and intensity of its long-term use.

Etizolam is cross-tolerant with all benzodiazepines and thienodiazepines, which means that after its consumption, all benzos and thienodiazepines will have a reduced effect.

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It should be noted that, as with benzodiazepines, stopping thienodiazepines suddenly can be dangerous, even life-threatening , for long-term users. Accordingly, people who are physically dependent on this substance are advised to reduce their dose by gradually reducing the amount taken each day for an extended period of time instead of stopping the substance abruptly.

" I tried - and got addicted - to etizolam before trying Xanax, and I find the two very different.

Level duration of action is about the same but the similarity stops there. The anxiolytic effect seems to me much more pronounced with etizolam, it has a little hypnotic side that is not disgusting when going to bed and above all, ESPECIALLY, I find it almost euphoric.

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I spent several months walking around with my vial of etizolam diluted in propylene glycol and I remember always having the smile, the peach, the desire to chat... much more than with n' any other benzo.

Well, the kiss kool effect is that you quickly end up living with the medoc, taking it at any time of the day ("trankil kopin g l'air sobre") and skipping times of the day, discussions... I still managed to come home from work with the wing of the car smashed and not having remembered how it had happened.

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